Wearing gauntlets of power should allow you to wield a two-handed weapon in one hand. This does remove a big downside of two-handed weapons - the danger of them becoming cursed - though; most late-game characters wielding a two-handed weapon are probably wearing gauntlets of power already.

Wearing gauntlets of power, you can snag a boulder and pull it with a grappling hook. If in Sokoban this incurs a penalty.

When wearing gauntlets of power, thrown javelins (or other spear-likes) continue flying after hitting monsters, and may damage monsters standing further back.